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Dendritic cell-associated B7-H3 suppresses the production of autoantibodies and renal inflammation in a mouse model of systemic lupus erythematosus

B7-H3 immune modulatory molecule has been implicated in the generation and pathogenesis of autoimmune diseases, the mechanism of action is less known. We explored the role of B7-H3 in the induction of autoantibodies and organ-directed inflammation in a murine systemic lupus erythematosus (SLE) model...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zheng, Xu, Xiao, Ze Xiu, Hu, Li, Fang, Xuan, Luo, Liqun, Chen, Lieping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529467/
https://ncbi.nlm.nih.gov/pubmed/31113935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1623-0
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