Enhancer architecture and essential core regulatory circuitry of chronic lymphocytic leukemia

Enhancer profiling is a powerful approach for discovering cis-regulatory elements that define the core transcriptional regulatory circuits of normal and malignant cells. Gene control through enhancer activity is often dominated by a subset of lineage-specific transcription factors. By integrating me...

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Publicat a:Cancer Cell
Autors principals: Ott, Christopher J., Federation, Alexander J., Schwartz, Logan S., Kasar, Siddha, Klitgaard, Josephine L., Lenci, Romina, Li, Qiyuan, Lawlor, Matthew, Fernandes, Stacey M., Souza, Amanda, Polaski, Donald, Gadi, Deepti, Freedman, Matthew L., Brown, Jennifer R., Bradner, James E.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298230/
https://ncbi.nlm.nih.gov/pubmed/30503705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.11.001
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