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Natural APOBEC3C variants can elicit differential HIV-1 restriction activity
BACKGROUND: The APOBEC3 (A3) family of DNA cytosine deaminases provides an innate barrier to infection by retroviruses including HIV-1. A total of five enzymes, A3C, A3D, A3F, A3G and A3H, are degraded by the viral accessory protein Vif and expressed at high levels in CD4+ T cells, the primary reser...
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| Publicado no: | Retrovirology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6297987/ https://ncbi.nlm.nih.gov/pubmed/30558640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-018-0459-5 |
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