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Intrinsic restriction activity by AID/APOBEC family of enzymes against the mobility of retroelements

A large portion of the mammalian genome is derived from ancient transposable elements. Retroelements, transported by an intracellular copy-and-paste process involving an RNA intermediate (retrotransposition), constitute a majority of these mobile genetic elements. Endogenous retroviruses are LTR-typ...

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Библиографические подробности
Главные авторы: Koito, Atsushi, Ikeda, Terumasa
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312301/
https://ncbi.nlm.nih.gov/pubmed/22479686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.1.3.17430
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