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Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity

APOBEC3s (A3s) are single-stranded DNA cytosine deaminases that provide innate immune defences against retroviruses and mobile elements. A3s are specific to eutherian mammals because no direct homologs exist at the syntenic genomic locus in metatherian (marsupial) or prototherian (monotreme) mammals...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ikeda, Terumasa, Shimoda, Mayuko, Ebrahimi, Diako, VandeBerg, John L., Harris, Reuben S., Koito, Atsushi, Maeda, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399452/
https://ncbi.nlm.nih.gov/pubmed/28429755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46719
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