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Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture

Recent electron microscopy data have revealed that cardiac mitochondria are not arranged in crystalline columns but are organised with several mitochondria aggregated into columns of varying sizes spanning the cell cross-section. This raises the question—how does the mitochondrial arrangement affect...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ghosh, Shouryadipta, Tran, Kenneth, Delbridge, Lea M. D., Hickey, Anthony J. R., Hanssen, Eric, Crampin, Edmund J., Rajagopal, Vijay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296675/
https://ncbi.nlm.nih.gov/pubmed/30517098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006640
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