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Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture

Recent electron microscopy data have revealed that cardiac mitochondria are not arranged in crystalline columns but are organised with several mitochondria aggregated into columns of varying sizes spanning the cell cross-section. This raises the question—how does the mitochondrial arrangement affect...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Ghosh, Shouryadipta, Tran, Kenneth, Delbridge, Lea M. D., Hickey, Anthony J. R., Hanssen, Eric, Crampin, Edmund J., Rajagopal, Vijay
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296675/
https://ncbi.nlm.nih.gov/pubmed/30517098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006640
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