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New Insights into the Bioenergetics of Mitochondrial Disorders Using Intracellular ATP Reporters

Mutations in mitochondrial DNA (mtDNA) cause impairment of ATP synthesis. It was hypothesized that high-energy compounds, such as ATP, are compartmentalized within cells and that different cell functions are sustained by different pools of ATP, some deriving from mitochondrial oxidative phosphorylat...

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Detalhes bibliográficos
Main Authors: Gajewski, Carl D., Yang, Lichuan, Schon, Eric A., Manfredi, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196555/
https://ncbi.nlm.nih.gov/pubmed/12972552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-12-0796
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