Insights From Computational Modeling Into the Contribution of Mechano-Calcium Feedback on the Cardiac End-Systolic Force-Length Relationship

In experimental studies on cardiac tissue, the end-systolic force-length relation (ESFLR) has been shown to depend on the mode of contraction: isometric or isotonic. The isometric ESFLR is derived from isometric contractions spanning a range of muscle lengths while the isotonic ESFLR is derived from...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Guidry, Megan E., Nickerson, David P., Crampin, Edmund J., Nash, Martyn P., Loiselle, Denis S., Tran, Kenneth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7273927/
https://ncbi.nlm.nih.gov/pubmed/32547426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00587
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