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NNK Reduction Pathway Gene Polymorphisms and Risk of Lung Cancer
The tobacco-specific nitrosamine NNK is a potent carcinogen found in tobacco smoke and implicated in the development of lung cancer. The major route of NNK metabolism is carbonyl reduction by AKR1C1, AKR1C2, CBR1, and 11p-HSD1 to form NNAL. This study investigated the potential role of variants in t...
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| Publicado no: | Mol Carcinog |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6296469/ https://ncbi.nlm.nih.gov/pubmed/24976539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22187 |
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