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Loss of Enzymes in the Bile Acid Synthesis Pathway Explains Differences in Bile Composition among Mammals

Bile acids are important for absorbing nutrients. Most mammals produce cholic and chenodeoxycholic bile acids. Here, we investigated genes in the bile acid synthesis pathway in four mammals that deviate from the usual mammalian bile composition. First, we show that naked-mole rats, elephants, and ma...

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Bibliografske podrobnosti
izdano v:Genome Biol Evol
Main Authors: Sharma, Virag, Hiller, Michael
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296402/
https://ncbi.nlm.nih.gov/pubmed/30388264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evy243
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