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Copper-mediated 1,2-bis(trifluoromethylation) of arynes

We herein describe an unprecedented 1,2-bis(trifluoromethylation) of arynes with [CuCF(3)] in the presence of an oxidant DDQ. The method allows the rapid construction of a new class of 1,2-bis(trifluoromethyl)arenes in one-step from aryne precursors under mild conditions. Its synthetic utility has b...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Yang, Xinkan, Tsui, Gavin Chit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296300/
https://ncbi.nlm.nih.gov/pubmed/30627405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03754j
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