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Mutations affecting spindle pole body and mitotic exit network function are synthetically lethal with a deletion of the nucleoporin NUP1 in S. cerevisiae

Nuclear pore complexes (NPCs) are embedded in the nuclear envelope of eukaryotic cells and function to regulate passage of macromolecules in and out of the nucleus. Nup1 is one of 30 nucleoporins comprising the NPC of the yeast Saccharomyces cerevisiae and is located on the nucleoplasmic face of the...

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Publicado en:Curr Genet
Autores principales: Harper, Nicola C., Al-Greene, Nicole T., Basrai, Munira A., Belanger, Kenneth D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296230/
https://ncbi.nlm.nih.gov/pubmed/18058101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-007-0168-4
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