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Spindle pole bodies function as signal amplifiers in the Mitotic Exit Network

The Mitotic Exit Network (MEN), a budding yeast Ras-like signal transduction cascade, translates nuclear position into a signal to exit from mitosis. Here we describe how scaffolding the MEN onto spindle pole bodies (SPB—centrosome equivalent) allows the MEN to couple the final stages of mitosis to...

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Publicado en:Mol Biol Cell
Autores principales: Campbell, Ian W., Zhou, Xiaoxue, Amon, Angelika
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185974/
https://ncbi.nlm.nih.gov/pubmed/32074005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-10-0584
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