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Alzheimer's disease in Down syndrome: An overlooked population for prevention trials
The discovery that adults with Down syndrome (DS) have neuropathological features identical to individuals with sporadic Alzheimer's disease (AD) played a key role in the identification of the amyloid precursor protein gene on chromosome 21 and resulted in the amyloid cascade hypothesis. Indivi...
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| 出版年: | Alzheimers Dement (N Y) |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6296162/ https://ncbi.nlm.nih.gov/pubmed/30581976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2018.10.006 |
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