Alzheimer's disease in Down syndrome: An overlooked population for prevention trials

The discovery that adults with Down syndrome (DS) have neuropathological features identical to individuals with sporadic Alzheimer's disease (AD) played a key role in the identification of the amyloid precursor protein gene on chromosome 21 and resulted in the amyloid cascade hypothesis. Indivi...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (N Y)
Main Authors: Strydom, André, Coppus, Antonia, Blesa, Rafael, Danek, Adrian, Fortea, Juan, Hardy, John, Levin, Johannes, Nuebling, Georg, Rebillat, Anne-Sophie, Ritchie, Craig, van Duijn, Cornelia, Zaman, Shahid, Zetterberg, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Perspective
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296162/
https://ncbi.nlm.nih.gov/pubmed/30581976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2018.10.006
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