Radiosynthesis of [(11)C]LY2795050 for Preclinical and Clinical PET Imaging Using Cu(II)-Mediated Cyanation

[Image: see text] Copper-mediated (11)C-cyanation reactions have enabled the synthesis of PET radiotracers from a range of readily available precursors and avoid the need to use more toxic Pd catalysts. In this work we adapt our recently developed (11)C-cyanation of arylpinacolboronate (BPin) esters...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Med Chem Lett
Prif Awduron: Yang, Lingyun, Brooks, Allen F., Makaravage, Katarina J., Zhang, Huibin, Sanford, Melanie S., Scott, Peter J. H., Shao, Xia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2018
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295869/
https://ncbi.nlm.nih.gov/pubmed/30613339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00460
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