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Selective Inhibition on Organic Cation Transporters by Carvedilol Protects Mice from Cisplatin-Induced Nephrotoxicity

PURPOSE: The organic cation transporters (OCTs) and multidrug and toxin extrusions (MATEs), located in the basolateral and apical membrane of proximal tubular cells respectively, are crucial determinants of renal elimination and/or toxicity of cationic drugs such as cisplatin. The purpose of this st...

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Detaylı Bibliyografya
Yayımlandı:Pharm Res
Asıl Yazarlar: Guo, Dong, Yang, Hong, Li, Qing, Bae, Hyo Jung, Obianom, Obinna, Zeng, Sujuan, Su, Tong, Polli, James E., Shu, Yan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295285/
https://ncbi.nlm.nih.gov/pubmed/30191328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2486-2
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