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Rethinking gamma-secretase inhibitors for treatment of non-small cell lung cancer: Is Notch the target?
Lung cancer is the leading cause of cancer deaths among men and women. Gamma-secretase inhibitors, a class of small molecule compounds that target the Notch pathway, have been tested to treat non-small cell lung cancer (NSCLC) in pre-clinical and clinical trials. Although ɣ-secretase inhibitors elic...
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| Udgivet i: | Clin Cancer Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295228/ https://ncbi.nlm.nih.gov/pubmed/30104200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1635 |
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