Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2

Saccharomyces cerevisiae target of rapamycin (TOR) complex 2 (TORC2) is an essential regulator of plasma membrane lipid and protein homeostasis. How TORC2 activity is modulated in response to changes in the status of the cell envelope is unclear. Here we document that TORC2 subunit Avo2 is a direct...

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Udgivet i:Genes Dev
Main Authors: Leskoske, Kristin L., Roelants, Françoise M., Emmerstorfer-Augustin, Anita, Augustin, Christoph M., Si, Edward P., Hill, Jennifer M., Thorner, Jeremy
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295167/
https://ncbi.nlm.nih.gov/pubmed/30478248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.318709.118
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