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Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2

Saccharomyces cerevisiae target of rapamycin (TOR) complex 2 (TORC2) is an essential regulator of plasma membrane lipid and protein homeostasis. How TORC2 activity is modulated in response to changes in the status of the cell envelope is unclear. Here we document that TORC2 subunit Avo2 is a direct...

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Publicado en:Genes Dev
Main Authors: Leskoske, Kristin L., Roelants, Françoise M., Emmerstorfer-Augustin, Anita, Augustin, Christoph M., Si, Edward P., Hill, Jennifer M., Thorner, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295167/
https://ncbi.nlm.nih.gov/pubmed/30478248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.318709.118
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