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The Curvature Induction of Surface-Bound Antimicrobial Peptides Piscidin 1 and Piscidin 3 Varies With Lipid Chain Length

The initial steps of membrane disruption by antimicrobial peptides (AMPs) involve binding to bacterial membranes in a surface-bound (S) orientation. To evaluate the effects of lipid composition on the S state, molecular dynamics simulations of the AMPs piscidin 1 (p1) and piscidin 3 (p3) were carrie...

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Bibliographic Details
Published in:J Membr Biol
Main Authors: Perrin, B. Scott, Sodt, Alexander J., Cotten, Myriam, Pastor, Richard W.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295150/
https://ncbi.nlm.nih.gov/pubmed/25292264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-014-9733-1
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