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Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood–brain barrier and blood–retina barrier development and maintenance

β-Catenin signaling controls the development and maintenance of the blood–brain barrier (BBB) and the blood–retina barrier (BRB), but the division of labor and degree of redundancy between the two principal ligand–receptor systems—the Norrin and Wnt7a/Wnt7b systems—are incompletely defined. Here, we...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Yanshu, Cho, Chris, Williams, John, Smallwood, Philip M., Zhang, Chi, Junge, Harald J., Nathans, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294914/
https://ncbi.nlm.nih.gov/pubmed/30478038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813217115
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