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Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1

NDP52 and TAX1BP1, two SKIP carboxyl homology (SKICH) domain-containing autophagy receptors, play crucial roles in selective autophagy. The autophagic functions of NDP52 and TAX1BP1 are regulated by TANK-binding kinase 1 (TBK1), which may associate with them through the adaptor NAP1. However, the mo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fu, Tao, Liu, Jianping, Wang, Yingli, Xie, Xingqiao, Hu, Shichen, Pan, Lifeng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294882/
https://ncbi.nlm.nih.gov/pubmed/30459273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811421115
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