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A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation
Programmed DNA double-strand breaks (DSBs) are required for meiotic recombination, but the number is strictly controlled because they are potentially harmful. Here we report a novel protein, Pars11, which is required for Spo11-dependent DSB formation in the protist Tetrahymena. Pars11 localizes to c...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294514/ https://ncbi.nlm.nih.gov/pubmed/30357385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky968 |
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