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Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks
Recent studies suggest that transcription takes place at DNA double-strand breaks (DSBs), that transcripts at DSBs are processed by Drosha and Dicer into damage-induced small RNAs (diRNAs), and that diRNAs are required for DNA repair. However, diRNAs have been mostly detected in reporter constructs...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294500/ https://ncbi.nlm.nih.gov/pubmed/30418607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1107 |
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