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Influence of pathway topology and functional class on the molecular evolution of human metabolic genes

Metabolic networks comprise thousands of enzymatic reactions functioning in a controlled manner and have been shaped by natural selection. Thanks to the genome data, the footprints of adaptive (positive) selection are detectable, and the strength of purifying selection can be measured. This has made...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Montanucci, Ludovica, Laayouni, Hafid, Dobon, Begoña, Keys, Kevin L., Bertranpetit, Jaume, Peretó, Juli
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294346/
https://ncbi.nlm.nih.gov/pubmed/30550546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208782
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