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Influence of pathway topology and functional class on the molecular evolution of human metabolic genes

Metabolic networks comprise thousands of enzymatic reactions functioning in a controlled manner and have been shaped by natural selection. Thanks to the genome data, the footprints of adaptive (positive) selection are detectable, and the strength of purifying selection can be measured. This has made...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Montanucci, Ludovica, Laayouni, Hafid, Dobon, Begoña, Keys, Kevin L., Bertranpetit, Jaume, Peretó, Juli
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294346/
https://ncbi.nlm.nih.gov/pubmed/30550546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208782
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