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Influence of pathway topology and functional class on the molecular evolution of human metabolic genes
Metabolic networks comprise thousands of enzymatic reactions functioning in a controlled manner and have been shaped by natural selection. Thanks to the genome data, the footprints of adaptive (positive) selection are detectable, and the strength of purifying selection can be measured. This has made...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294346/ https://ncbi.nlm.nih.gov/pubmed/30550546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208782 |
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