Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma

Diversification at the transcriptome 3′end is an important and evolutionarily conserved layer of gene regulation associated with differentiation and dedifferentiation processes. Here, we identify extensive transcriptome 3′end-alterations in neuroblastoma, a tumour entity with a paucity of recurrent...

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Publicado en:Nat Commun
Autores principales: Ogorodnikov, Anton, Levin, Michal, Tattikota, Surendra, Tokalov, Sergey, Hoque, Mainul, Scherzinger, Denise, Marini, Federico, Poetsch, Ansgar, Binder, Harald, Macher-Göppinger, Stephan, Probst, Hans Christian, Tian, Bin, Schaefer, Michael, Lackner, Karl J., Westermann, Frank, Danckwardt, Sven
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294251/
https://ncbi.nlm.nih.gov/pubmed/30552333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07580-5
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