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Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies

The small intestine plays an important role in the absorption and metabolism of oral drugs. In the current evaluation system, it is difficult to predict the precise absorption and metabolism of oral drugs. In this study, we generated small intestinal epithelial-like cells from human induced pluripot...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Negoro, Ryosuke, Takayama, Kazuo, Kawai, Kanae, Harada, Kazuo, Sakurai, Fuminori, Hirata, Kazumasa, Mizuguchi, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294172/
https://ncbi.nlm.nih.gov/pubmed/30472010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.10.019
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