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Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies

The small intestine plays an important role in the absorption and metabolism of oral drugs. In the current evaluation system, it is difficult to predict the precise absorption and metabolism of oral drugs. In this study, we generated small intestinal epithelial-like cells from human induced pluripot...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Negoro, Ryosuke, Takayama, Kazuo, Kawai, Kanae, Harada, Kazuo, Sakurai, Fuminori, Hirata, Kazumasa, Mizuguchi, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294172/
https://ncbi.nlm.nih.gov/pubmed/30472010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.10.019
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