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IQGAP1 Maintains Pancreatic Ductal Adenocarcinoma Clonogenic Growth and Metastasis
OBJECTIVES: IQ motif containing GTPase activating protein 1 (IQGAP1) acts as a scaffold for aberrant MAPK signaling driven by KRAS mutations in pancreatic ductal adenocarcinoma (PDAC). We determined the role of IQGAP1 in clonogenic growth and metastasis in PDAC. METHODS: We inhibited IQGAP1 expressi...
Tallennettuna:
| Julkaisussa: | Pancreas |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6293988/ https://ncbi.nlm.nih.gov/pubmed/30540680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000001198 |
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