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Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma

Pancreatic cancer is the only major cancer with very low survival rates (1%). It is the fourth leading cause of cancer-related death. Hyperactivated growth hormone receptor (GHR) levels have been shown to increase the risk of cancer in general and this pathway is a master regulator of key cellular f...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Subramani, Ramadevi, Lopez-Valdez, Rebecca, Salcido, Alyssa, Boopalan, Thiyagarajan, Arumugam, Arunkumar, Nandy, Sushmita, Lakshmanaswamy, Rajkumar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221692/
https://ncbi.nlm.nih.gov/pubmed/25301264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.61
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