Impact of index hopping and bias towards the reference allele on accuracy of genotype calls from low-coverage sequencing

BACKGROUND: Inherent sources of error and bias that affect the quality of sequence data include index hopping and bias towards the reference allele. The impact of these artefacts is likely greater for low-coverage data than for high-coverage data because low-coverage data has scant information and m...

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Библиографические подробности
Опубликовано в: :Genet Sel Evol
Главные авторы: Ros-Freixedes, Roger, Battagin, Mara, Johnsson, Martin, Gorjanc, Gregor, Mileham, Alan J., Rounsley, Steve D., Hickey, John M.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293637/
https://ncbi.nlm.nih.gov/pubmed/30545283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-018-0436-4
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