Impact of index hopping and bias towards the reference allele on accuracy of genotype calls from low-coverage sequencing

BACKGROUND: Inherent sources of error and bias that affect the quality of sequence data include index hopping and bias towards the reference allele. The impact of these artefacts is likely greater for low-coverage data than for high-coverage data because low-coverage data has scant information and m...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Genet Sel Evol
Glavni autori: Ros-Freixedes, Roger, Battagin, Mara, Johnsson, Martin, Gorjanc, Gregor, Mileham, Alan J., Rounsley, Steve D., Hickey, John M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293637/
https://ncbi.nlm.nih.gov/pubmed/30545283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-018-0436-4
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items