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Hybrid peeling for fast and accurate calling, phasing, and imputation with sequence data of any coverage in pedigrees
BACKGROUND: In this paper, we extend multi-locus iterative peeling to provide a computationally efficient method for calling, phasing, and imputing sequence data of any coverage in small or large pedigrees. Our method, called hybrid peeling, uses multi-locus iterative peeling to estimate shared chro...
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| Udgivet i: | Genet Sel Evol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6299538/ https://ncbi.nlm.nih.gov/pubmed/30563452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-018-0438-2 |
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