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Hybrid peeling for fast and accurate calling, phasing, and imputation with sequence data of any coverage in pedigrees

BACKGROUND: In this paper, we extend multi-locus iterative peeling to provide a computationally efficient method for calling, phasing, and imputing sequence data of any coverage in small or large pedigrees. Our method, called hybrid peeling, uses multi-locus iterative peeling to estimate shared chro...

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Bibliografiske detaljer
Udgivet i:Genet Sel Evol
Main Authors: Whalen, Andrew, Ros-Freixedes, Roger, Wilson, David L., Gorjanc, Gregor, Hickey, John M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299538/
https://ncbi.nlm.nih.gov/pubmed/30563452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-018-0438-2
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