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Family-specific genotype arrays increase the accuracy of pedigree-based imputation at very low marker densities

Abstract Background In this paper, we evaluate the performance of using family-specific low-density genotype arrays to increase the accuracy of pedigree-based imputation. Genotype imputation is a widely used tool that decreases the costs of genotyping a population by genotyping the majority of indiv...

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Bibliographic Details
Main Authors: Andrew Whalen, Gregor Gorjanc, John M. Hickey
Format: Artigo
Language:Alemão
Published: BMC 2019-06-01
Series:Genetics Selection Evolution
Online Access:http://link.springer.com/article/10.1186/s12711-019-0478-2
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