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Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery

The dopaminergic hypothesis of schizophrenia (SZ) postulates that positive symptoms of SZ, in particular psychosis, are due to disturbed neurotransmission via the dopamine (DA) receptor D2 (DRD2). However, DA is a reactive molecule that yields various oxidative species, and thus has important non-re...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Kos, Mark Z., Duan, Jubao, Sanders, Alan R., Blondell, Lucy, Drigalenko, Eugene I., Carless, Melanie A., Gejman, Pablo V., Göring, Harald H. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293320/
https://ncbi.nlm.nih.gov/pubmed/30546022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0325-1
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