Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery

The dopaminergic hypothesis of schizophrenia (SZ) postulates that positive symptoms of SZ, in particular psychosis, are due to disturbed neurotransmission via the dopamine (DA) receptor D2 (DRD2). However, DA is a reactive molecule that yields various oxidative species, and thus has important non-re...

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Bibliografiska uppgifter
I publikationen:Transl Psychiatry
Huvudupphovsmän: Kos, Mark Z., Duan, Jubao, Sanders, Alan R., Blondell, Lucy, Drigalenko, Eugene I., Carless, Melanie A., Gejman, Pablo V., Göring, Harald H. H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293320/
https://ncbi.nlm.nih.gov/pubmed/30546022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0325-1
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