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Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants

We searched a gene expression dataset comprised of 634 schizophrenia (SZ) cases and 713 controls for expression outliers (i.e., extreme tails of the distribution of transcript expression values) with SZ cases overrepresented compared with controls. These outlier genes were enriched for brain express...

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Библиографические подробности
Опубликовано в: :Hum Mol Genet
Главные авторы: Duan, Jubao, Sanders, Alan R., Moy, Winton, Drigalenko, Eugene I., Brown, Eric C., Freda, Jessica, Leites, Catherine, Göring, Harald H. H., Gejman, Pablo V.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512633/
https://ncbi.nlm.nih.gov/pubmed/26022996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv199
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