Doxycycline attenuates cisplatin-induced acute kidney injury through pleiotropic effects

Cisplatin (CDDP) is a widely-used chemotherapeutic drug for solid tumors, but its nephrotoxicity is a major dose-limiting factor. Doxycycline (Dox) is a tetracycline antibiotic that has been commonly used in a variety of infections. Dox has been shown to possess several other properties, including a...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Nakagawa, Terumasa, Kakizoe, Yutaka, Iwata, Yasunobu, Miyasato, Yoshikazu, Mizumoto, Teruhiko, Adachi, Masataka, Izumi, Yuichiro, Kuwabara, Takashige, Suenaga, Naoki, Narita, Yuki, Jono, Hirofumi, Saito, Hideyuki, Kitamura, Kenichiro, Mukoyama, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293283/
https://ncbi.nlm.nih.gov/pubmed/30043627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00648.2017
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