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Integrating Experiment and Theory to Understand TCR-pMHC Dynamics

The conformational dynamism of proteins is well established. Rather than having a single structure, proteins are more accurately described as a conformational ensemble that exists across a rugged energy landscape, where different conformational sub-states interconvert. The interaction between αβ T c...

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Vydáno v:Front Immunol
Hlavní autoři: Buckle, Ashley M., Borg, Natalie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293202/
https://ncbi.nlm.nih.gov/pubmed/30581442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02898
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