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Integrating Experiment and Theory to Understand TCR-pMHC Dynamics

The conformational dynamism of proteins is well established. Rather than having a single structure, proteins are more accurately described as a conformational ensemble that exists across a rugged energy landscape, where different conformational sub-states interconvert. The interaction between αβ T c...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Buckle, Ashley M., Borg, Natalie A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293202/
https://ncbi.nlm.nih.gov/pubmed/30581442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02898
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