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The formation of chromatin domains involves a primary step based on the 3-D structure of DNA
The general model presented here for the formation of chromatin domains, LADs and TADs, is primarily based on the 3-D structures of the corresponding DNA sequences, the GC-poor and GC-rich isochores. Indeed, the low-heterogeneity GC-poor isochores locally are intrinsically stiff and curved because o...
保存先:
| 出版年: | Sci Rep |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6292937/ https://ncbi.nlm.nih.gov/pubmed/30546050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35851-0 |
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