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The “Genomic Code”: DNA Pervasively Moulds Chromatin Structures Leaving no Room for “Junk”

The chromatin of the human genome was analyzed at three DNA size levels. At the first, compartment level, two “gene spaces” were found many years ago: A GC-rich, gene-rich “genome core” and a GC-poor, gene-poor “genome desert”, the former corresponding to open chromatin centrally located in the inte...

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Dettagli Bibliografici
Pubblicato in:Life (Basel)
Autore principale: Bernardi, Giorgio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070607/
https://ncbi.nlm.nih.gov/pubmed/33924668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life11040342
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