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Impact of Chromatin Structures on DNA Processing for Genomic Analyses

Chromatin has an impact on recombination, repair, replication, and evolution of DNA. Here we report that chromatin structure also affects laboratory DNA manipulation in ways that distort the results of chromatin immunoprecipitation (ChIP) experiments. We initially discovered this effect at the Sacch...

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Detalhes bibliográficos
Main Authors: Teytelman, Leonid, Özaydın, Bilge, Zill, Oliver, Lefrançois, Philippe, Snyder, Michael, Rine, Jasper, Eisen, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725323/
https://ncbi.nlm.nih.gov/pubmed/19693276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006700
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