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Impact of Chromatin Structures on DNA Processing for Genomic Analyses

Chromatin has an impact on recombination, repair, replication, and evolution of DNA. Here we report that chromatin structure also affects laboratory DNA manipulation in ways that distort the results of chromatin immunoprecipitation (ChIP) experiments. We initially discovered this effect at the Sacch...

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Autors principals: Teytelman, Leonid, Özaydın, Bilge, Zill, Oliver, Lefrançois, Philippe, Snyder, Michael, Rine, Jasper, Eisen, Michael B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725323/
https://ncbi.nlm.nih.gov/pubmed/19693276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006700
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