A yellow fever–Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice

The recent Zika virus (ZIKV) epidemic in the Americas led to an intense search for therapeutics and vaccines. Here we report the engineering of a chimeric virus vaccine candidate (YF-ZIKprM/E) by replacing the antigenic surface glycoproteins and the capsid anchor of YFV-17D with those of a prototypi...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Kum, Dieudonné B., Mishra, Niraj, Boudewijns, Robbert, Gladwyn-Ng, Ivan, Alfano, Christian, Ma, Ji, Schmid, Michael A., Marques, Rafael E., Schols, Dominique, Kaptein, Suzanne, Nguyen, Laurent, Neyts, Johan, Dallmeier, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292895/
https://ncbi.nlm.nih.gov/pubmed/30564463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-018-0092-2
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