A novel therapeutic HBV vaccine candidate induces strong polyfunctional cytotoxic T cell responses in mice

BACKGROUND & AIMS: Current standard-of-care suppresses HBV replication, but does not lead to a functional cure. Treatment aiming to cure chronic hepatitis B (CHB) is believed to require the induction of strong cellular immune responses, such as by therapeutic vaccination. METHODS: We designed a...

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Detalhes bibliográficos
Publicado no:JHEP Rep
Main Authors: Boudewijns, Robbert, Ma, Ji, Neyts, Johan, Dallmeier, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203848/
https://ncbi.nlm.nih.gov/pubmed/34159304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2021.100295
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