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A novel therapeutic HBV vaccine candidate induces strong polyfunctional cytotoxic T cell responses in mice
BACKGROUND & AIMS: Current standard-of-care suppresses HBV replication, but does not lead to a functional cure. Treatment aiming to cure chronic hepatitis B (CHB) is believed to require the induction of strong cellular immune responses, such as by therapeutic vaccination. METHODS: We designed a...
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| Publicat a: | JHEP Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8203848/ https://ncbi.nlm.nih.gov/pubmed/34159304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2021.100295 |
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