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A comprehensive ensemble model for comparing the allosteric effect of ordered and disordered proteins
Intrinsically disordered proteins/regions (IDPs/IDRs) are prevalent in allosteric regulation. It was previously thought that intrinsic disorder is favorable for maximizing the allosteric coupling. Here, we propose a comprehensive ensemble model to compare the roles of both order-order transition and...
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| 發表在: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6292653/ https://ncbi.nlm.nih.gov/pubmed/30507941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006393 |
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