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A comprehensive ensemble model for comparing the allosteric effect of ordered and disordered proteins

Intrinsically disordered proteins/regions (IDPs/IDRs) are prevalent in allosteric regulation. It was previously thought that intrinsic disorder is favorable for maximizing the allosteric coupling. Here, we propose a comprehensive ensemble model to compare the roles of both order-order transition and...

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書目詳細資料
發表在:PLoS Comput Biol
Main Authors: Zhang, Luhao, Li, Maodong, Liu, Zhirong
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292653/
https://ncbi.nlm.nih.gov/pubmed/30507941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006393
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