mTHPC-loaded extracellular vesicles outperform liposomal and free mTHPC formulations by an increased stability, drug delivery efficiency and cytotoxic effect in tridimensional model of tumors

Efficient photodynamic therapy with meta-tetra(hydroxyphenyl)chlorine requires the application of specific nanoformulations. mTHPC liposomal formulation (Foslip(®)) demonstrated favorable pharmacokinetics properties. However, rapid liposomes destruction in circulation and rapid mTHPC release impedes...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Millard, Marie, Yakavets, Ilya, Piffoux, Max, Brun, Amanda, Gazeau, Florence, Guigner, Jean-Michel, Jasniewski, Jordane, Lassalle, Henri-Pierre, Wilhelm, Claire, Bezdetnaya, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292368/
https://ncbi.nlm.nih.gov/pubmed/30785308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1513609
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