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N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer’s Disease Rat Model

We have previously reported that primary hippocampal neurons exposed to synaptotoxic amyloid beta oligomers (AβOs), which are likely causative agents of Alzheimer’s disease (AD), exhibit abnormal Ca(2+) signals, mitochondrial dysfunction and defective structural plasticity. Additionally, AβOs-expose...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: More, Jamileth, Galusso, Nadia, Veloso, Pablo, Montecinos, Luis, Finkelstein, José Pablo, Sanchez, Gina, Bull, Ricardo, Valdés, José Luis, Hidalgo, Cecilia, Paula-Lima, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291746/
https://ncbi.nlm.nih.gov/pubmed/30574085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00399
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