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N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer’s Disease Rat Model
We have previously reported that primary hippocampal neurons exposed to synaptotoxic amyloid beta oligomers (AβOs), which are likely causative agents of Alzheimer’s disease (AD), exhibit abnormal Ca(2+) signals, mitochondrial dysfunction and defective structural plasticity. Additionally, AβOs-expose...
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| Publicado no: | Front Aging Neurosci |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291746/ https://ncbi.nlm.nih.gov/pubmed/30574085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00399 |
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