N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer’s Disease Rat Model

We have previously reported that primary hippocampal neurons exposed to synaptotoxic amyloid beta oligomers (AβOs), which are likely causative agents of Alzheimer’s disease (AD), exhibit abnormal Ca(2+) signals, mitochondrial dysfunction and defective structural plasticity. Additionally, AβOs-expose...

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Bibliografiska uppgifter
I publikationen:Front Aging Neurosci
Huvudupphovsmän: More, Jamileth, Galusso, Nadia, Veloso, Pablo, Montecinos, Luis, Finkelstein, José Pablo, Sanchez, Gina, Bull, Ricardo, Valdés, José Luis, Hidalgo, Cecilia, Paula-Lima, Andrea
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291746/
https://ncbi.nlm.nih.gov/pubmed/30574085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00399
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