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Pharmacokinetics of sodium thiosulfate in Guinea pig perilymph following middle ear application

HYPOTHESIS: To determine the pharmacokinetics of sodium thiosulfate in the inner ear perilymph following middle ear application in Guinea pigs. BACKGROUND: Cisplatin chemotherapy is often associated with a dose-dependent high frequency sensorineural hearing loss. Sodium thiosulfate has been shown to...

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Bibliografiska uppgifter
I publikationen:J Otol
Huvudupphovsmän: Schroeder, Ronald J., Audlin, Jason, Luo, Juntao, Nicholas, Brian D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Chinese PLA General Hospital 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291635/
https://ncbi.nlm.nih.gov/pubmed/30559765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joto.2017.12.001
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